Single-Molecule Sensing: Light waves meet molecular machines

Main list: Photonics Seminar

Abstract

Single-molecule techniques continue to transform imaging, biophysics and, more recently, optical sensing. I will introduce a new class of label-free micro and nanosensors that are starting to emerge and that allow us to observe dynamic processes at the single molecule level directly with light, with unprecedented spatial- and temporal resolution, and without significantly affecting the natural and functional movements of the molecules. Initial demonstration include single ion sensing, and visualisation of functional movements of enzymes directly with light.

This new class of sensors combine optically resonant dielectric microcavities with plasmonically resonant metal nanostructures to enable detection at the nanoscale with extraordinary sensitivity. These optoplasmonic sensors by virtue of their small interaction length probe light–matter interactions over a dynamic range often inaccessible by other optical techniques. They can be used to study dynamic processes that can span a range from less than 10−9s to more than 10^3s.

  • Speaker

    Frank Vollmer
    University of Exeter

  • Venue

    School of Physics and Astronomy

  • Venue Info

    Theatre C

  • Date

    November 14, 2019

  • Time

    From: 10h00 To: 11h00

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