Lewis Acidic Boranes In Synthesis And Catalysis

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Abstract

Dr Rebecca Melen
Cardiff
LEWIS ACIDIC BORANES IN SYNTHESIS AND CATALYSIS Rebecca L. Melen 1* 1 School of Chemistry, Cardiff University, Main Building, Park Place, Cardiff, CF10 3AT, UK Email: MelenR@cardiff.ac.uk As main group chemistry, in particular boron chemistry, has expanded and developed over the past 20 years, one reagent has risen to prominence as well. Tris(pentafluorophenyl)borane, B(C 6F5)3, (commonly known as BCF) has demonstrated extensive applications in a wide variety of chemistry, including borylations, hydrogenations, hydrosilylations, frustrated Lewis pair chemistry, Lewis acid catalysis and more. 1 The high Lewis acidity of B(C 6F5)3 is achieved from the electronic effects of its three C 6F5 rings, rendering it a versatile reagent for a great number of reactions. The talk will show our recent uses of Lewis acidic boranes in organic synthesis and catalysis (Figure 1) and will also focus on our latest advances in novel borane and borocation usage. 2-5 Figure 1
1. G. Erker, Dalton Trans ., 2005 , 1883; G. C. Welch, R. R. San Juan, J. D. Masuda, D. W. Stephan, Science, 2006, 314, 1124; R. L. Melen, Chem. Commun ., 2014 , 50 , 1161. 2. L. C. Wilkins, B. A. R. G ΓΌnther , M. Walther, J. R. Lawson, T. Wirth, R. L. Melen, Angew. Chem. Int. Ed ., 2016, 55, 11292. 3. I. Khan, B. G. Reed -Berendt, R. L. Melen, L. C. Morrill, Angew. Chem. Int. Ed ., 2018 , 57 , 12356. 4. I. Khan, M. Manzotti, G. J. Tizzard, S. J. Coles, R. L. Melen , L. C. Morrill, ACS Catalysis , 2017 , 7, 7748. 5. M. Santi, D. M. C. Ould, J. Wenz, Y. Soltani, R. L. Melen, T. Wirth, Angew. Chem. Int. Ed ., 2019 , 58 , 7861.
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  • Venue

    Theatre C, Purdie

  • Date

    September 25, 2019

  • Time

    From: 15h30 To: 16h30

  • Sponsor

    University of St Andrews
    The oldest university in Scotland, with international renown for both research and education of undergraduates and postgraduates.

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